BIGG

The use of molecular line probe assays for the detection of resistance to second-line anti-tuberculosis drugs: policy guidance

World Health Organization.

This document provides a summary of the evidence and recommendations for the use of SL-LPA for the detection of mutations associated with resistance to fluoroquinolones and SLID in patients with RR-TB and/or MDR-TB. The objectives of this policy guidance are to assess and compare the diagnostic accuracy ...

Tuberculosis Resistente a Múltiples Medicamentos/diagnóstico, Antibióticos Antituberculosos/farmacología, Técnicas de Sonda Molecular, Pruebas de Sensibilidad Microbiana, Fluoroquinolonas/uso terapéutico, Farmacorresistencia Bacteriana/genética, Genotipo, Mutación, Tuberculosis Resistente a Múltiples Medicamentos/genética, Mycobacterium tuberculosis/efectos de los fármacos, Mycobacterium tuberculosis/genética

Texto completo

Noncommercial culture and drug-susceptibility testing methods for screening patients at risk for multidrug-resistant tuberculosis: policy statement

Commercial liquid culture systems and molecular line-probe assays have been endorsed by the World Health Organization (WHO) as gold standards for rapid detection of multidrug-resistant (MDR) tuberculosis (TB); however, because of technical complexity, cost and the requirement for sophisticated laboratory...